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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICK
All Species:
20
Human Site:
S376
Identified Species:
40
UniProt:
Q9UPZ9
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPZ9
NP_055735.1
632
71427
S376
P
S
P
L
L
F
P
S
L
H
N
K
H
P
Q
Chimpanzee
Pan troglodytes
XP_001154965
633
71532
S377
P
S
P
L
L
F
P
S
L
H
N
K
H
P
Q
Rhesus Macaque
Macaca mulatta
XP_001100720
616
68399
S360
P
S
P
L
L
F
P
S
L
H
N
K
N
P
Q
Dog
Lupus familis
XP_538964
685
76968
S429
P
S
P
L
L
F
P
S
L
H
T
K
K
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKV2
629
70573
S373
P
S
P
P
F
F
P
S
L
H
N
K
N
L
Q
Rat
Rattus norvegicus
Q62726
629
70550
S373
P
N
P
P
F
F
P
S
L
H
N
K
N
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514373
624
70740
L370
P
Q
Q
K
Q
Q
Q
L
F
P
S
I
S
K
N
Chicken
Gallus gallus
Frog
Xenopus laevis
P23437
297
33852
V44
L
D
T
E
T
E
G
V
P
S
T
A
I
R
E
Zebra Danio
Brachydanio rerio
NP_956240
633
71283
R376
L
M
G
L
K
N
G
R
R
R
W
G
Q
T
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392924
569
65790
P316
N
K
V
N
L
P
P
P
V
L
K
S
Y
N
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200813
576
64528
A323
S
A
K
R
R
V
L
A
E
S
K
P
A
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43294
443
50877
D189
S
L
Y
T
P
A
V
D
M
W
A
V
G
A
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
86.8
86.1
N.A.
86.3
85.5
N.A.
56.6
N.A.
23.1
47
N.A.
N.A.
45.8
N.A.
48.5
Protein Similarity:
100
99.5
90
89.4
N.A.
92
91.6
N.A.
68.8
N.A.
32.1
60.5
N.A.
N.A.
61.3
N.A.
62.1
P-Site Identity:
100
100
93.3
86.6
N.A.
73.3
60
N.A.
6.6
N.A.
0
6.6
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
80
73.3
N.A.
13.3
N.A.
6.6
6.6
N.A.
N.A.
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
9
0
9
0
0
9
9
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
9
0
9
0
0
9
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
17
50
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
17
0
0
0
0
9
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
50
0
0
17
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
9
% I
% Lys:
0
9
9
9
9
0
0
0
0
0
17
50
9
9
0
% K
% Leu:
17
9
0
42
42
0
9
9
50
9
0
0
0
17
0
% L
% Met:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
9
9
0
9
0
9
0
0
0
0
42
0
25
9
17
% N
% Pro:
59
0
50
17
9
9
59
9
9
9
0
9
0
42
9
% P
% Gln:
0
9
9
0
9
9
9
0
0
0
0
0
9
0
42
% Q
% Arg:
0
0
0
9
9
0
0
9
9
9
0
0
0
9
0
% R
% Ser:
17
42
0
0
0
0
0
50
0
17
9
9
9
0
9
% S
% Thr:
0
0
9
9
9
0
0
0
0
0
17
0
0
9
0
% T
% Val:
0
0
9
0
0
9
9
9
9
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _